Born in the Bronx in 1954, D'Alessio's artistic journey began at an early age when he was accepted into the High School of Music and Art in New York City (the movie ''Fame'' school). He went on to graduate from Fordham University (1975), studied at New York's School of Visual Arts (1976), and attended the renowned Art Students' League (1977). D'Alessio's professional art career began in Manhattan as art production manager for Bloomingdales. His last years in New York City were devoted to a collaboration with artist Stanley Landsman who recalled his experience with D'Alessio: ''I've never seen such an abundance of talent infused into someone as young as Carlo; his command of technique is extraordinary.''
D'Alessio paints with a distinctive method that produces a stunning visual impact. By layering acrylic paint with varnish, he creates a brilliant three-dimensional effect that mimics changes in natural light. Over the course of his 35-year career as a visual artist, D'Alessio has perfected his understanding of perspective and shadow, further enhancing the illusion of his paintings.